Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Antibody
299€ (50 µl)
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935106861
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name
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx402510
tested applications
ELISA, IF/ICC
Description
Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human ERBB3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) Immunogen: A synthesized peptide derived from human ErbB3 |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21860 |
| NCBI Accession | NP_001005915.1, NP_001973.2 |
| Background | Antibody anti-ERBB3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1(NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase(PubMed:20682778). May also be activated by CSPG5(PubMed:15358134).
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