ERBB3 antibody
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935106861
info@markelab.com
name
ERBB3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02828
tested applications
ELISA, IHC
Description
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1(NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase(PubMed:20682778). May also be activated by CSPG5(PubMed:15358134).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (ERBB3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P21860 |
| Gene ID | 2065 |
| Alias | Receptor tyrosine-protein kinase erbB-3,Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3,ERBB3,HER3 |
| Background | Antibody anti-ERBB3 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
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ERBB3 antibody
Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1(NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase(PubMed:20682778). May also be activated by CSPG5(PubMed:15358134).
Ver Producto