Receptor tyrosine-protein kinase erbB-3 (ERBB3) Antibody
286€ (0.1 mg)
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935106861
info@markelab.com
name
Receptor tyrosine-protein kinase erbB-3 (ERBB3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx347341
tested applications
FCM
Description
Receptor tyrosine-protein kinase erbB-3 (ERBB3) Antibody is a Mouse Monoclonal antibody for Receptor tyrosine-protein kinase erbB-3 (ERBB3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Receptor Tyrosine-Protein Kinase ERBB3 (ERBB3) Immunogen: HER3-transfected CHO cells. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | FCM: 1-5 μg/ml. Optimal dilutions/concentrations should be determined by the end user.. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a Kappa |
| Clone ID | U053 |
| Purification | Purified by Protein A affinity chromatography. |
| Size 1 | 0.1 mg |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.4, containing 15 mM sodium azide. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P21860 |
| Gene ID | 2065 |
| Background | Antibody anti-ERBB3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1(NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase(PubMed:20682778). May also be activated by CSPG5(PubMed:15358134).
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