Receptor-Type Tyrosine-Protein Phosphatase Eta (PTPRJ) Antibody
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Description
Receptor-Type Tyrosine-Protein Phosphatase Eta (PTPRJ) Antibody is a Mouse Monoclonal antibody for the detection of Receptor-Type Tyrosine-Protein Phosphatase Eta (PTPRJ) in Human samples.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Receptor-Type Tyrosine-Protein Phosphatase Eta (PTPRJ) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | U290 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, 0.09% Sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12913 |
| Gene ID | 5795 |
| NCBI Accession | NP_001091973.1 |
| Alias | DEP1,SCC1,CD148,THC10,HPTPeta,R-PTP-J,HPTP eta,R-PTP-ETA,Protein-tyrosine phosphatase receptor type J,Density-enhanced phosphatase 1,Protein-tyrosine phosphatase eta,Receptor-type tyrosine-protein phosphatase eta |
| Background | Antibody anti-PTPRJ |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Human PTPRJ (Protein Tyrosine Phosphatase Receptor Type J) ELISA Kit
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PTPRJ antibody
Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, RET(variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor(TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells(APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.
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