Rat Vasopressin V2 Receptor (AVPR2) ELISA Kit

Este producto es parte de AVPR - Arginine Vasopressin Receptor
Rat Vasopressin V2 Receptor (AVPR2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AVPR2

proveedor

Abbexa

reference

abx552814

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Vasopressin V2 Receptor (AVPR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Vasopressin V2 Receptor (AVPR2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

AVPR2 is another G protein-coupled receptor activated by arginine vasopressin (AVP). It is primarily expressed in the kidneys, where it plays a critical role in regulating water reabsorption and maintaining fluid balance. AVPR2 couples to Gs proteins, activating adenylate cyclase and increasing intracellular cAMP levels, which promotes the insertion of aquaporin water channels into the cell membrane, allowing for water reabsorption. This process is crucial for maintaining osmotic balance and preventing dehydration. AVPR2 is also involved in regulating blood pressure by modulating vascular smooth muscle tone. Mutations in the AVPR2 gene are the cause of X-linked nephrogenic diabetes insipidus, a condition characterized by the kidneys' inability to concentrate urine, leading to excessive thirst and urination. AVPR2 antagonists are being developed for the treatment of conditions such as diabetes insipidus and certain forms of heart failure, where controlling water retention and blood pressure is critical.

Características del producto

category

ELISA Kits


immunogen target

Vasopressin V2 Receptor (AVPR2)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

AVPR2,AVPR,ADHR,DIR3,antidiuretic hormone receptor,renal-type arginine vasopressin receptor,DI1,DIR3, NDI, NDI1, V2R


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AVPR2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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