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Rat Vasopressin V2 Receptor (AVPR2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits AVPR2
proveedor
Abbexareference
abx552814Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Vasopressin V2 Receptor (AVPR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Vasopressin V2 Receptor (AVPR2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
AVPR2 is another G protein-coupled receptor activated by arginine vasopressin (AVP). It is primarily expressed in the kidneys, where it plays a critical role in regulating water reabsorption and maintaining fluid balance. AVPR2 couples to Gs proteins, activating adenylate cyclase and increasing intracellular cAMP levels, which promotes the insertion of aquaporin water channels into the cell membrane, allowing for water reabsorption. This process is crucial for maintaining osmotic balance and preventing dehydration. AVPR2 is also involved in regulating blood pressure by modulating vascular smooth muscle tone. Mutations in the AVPR2 gene are the cause of X-linked nephrogenic diabetes insipidus, a condition characterized by the kidneys' inability to concentrate urine, leading to excessive thirst and urination. AVPR2 antagonists are being developed for the treatment of conditions such as diabetes insipidus and certain forms of heart failure, where controlling water retention and blood pressure is critical.
Características del producto
category
ELISA Kits
immunogen target
Vasopressin V2 Receptor (AVPR2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
AVPR2,AVPR,ADHR,DIR3,antidiuretic hormone receptor,renal-type arginine vasopressin receptor,DI1,DIR3, NDI, NDI1, V2R
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
AVPR2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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