Mouse Vasopressin V2 Receptor (AVPR2) ELISA Kit
715€ (96 tests)
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name
Mouse Vasopressin V2 Receptor (AVPR2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx153696
tested applications
ELISA
Description
Mouse Vasopressin V2 Receptor (AVPR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Vasopressin V2 Receptor (AVPR2) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Arginine Vasopressin Receptor 2 (AVPR2)
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Vasopressin V2 Receptor (AVPR2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.12 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | AVPR2,AVPR,ADHR,DIR3,antidiuretic hormone receptor,renal-type arginine vasopressin receptor,DI1,DIR3, NDI, NDI1, V2R |
| Background | Elisa kits for AVPR2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AVPR2 is another G protein-coupled receptor activated by arginine vasopressin (AVP). It is primarily expressed in the kidneys, where it plays a critical role in regulating water reabsorption and maintaining fluid balance. AVPR2 couples to Gs proteins, activating adenylate cyclase and increasing intracellular cAMP levels, which promotes the insertion of aquaporin water channels into the cell membrane, allowing for water reabsorption. This process is crucial for maintaining osmotic balance and preventing dehydration. AVPR2 is also involved in regulating blood pressure by modulating vascular smooth muscle tone. Mutations in the AVPR2 gene are the cause of X-linked nephrogenic diabetes insipidus, a condition characterized by the kidneys' inability to concentrate urine, leading to excessive thirst and urination. AVPR2 antagonists are being developed for the treatment of conditions such as diabetes insipidus and certain forms of heart failure, where controlling water retention and blood pressure is critical.
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