Rat UBX Domain-Containing Protein 11 (UBXN11) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for UBXN11
proveedor
Abbexareference
abx552418Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat UBX Domain-Containing Protein 11 (UBXN11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat UBX Domain-Containing Protein 11 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
UBX domain protein 11 (UBXN11) is a member of the UBX family of proteins that interact with p97/VCP, a central ATPase in protein degradation and cellular quality control pathways The UBX domain in UBXN11 enables its binding to p97, facilitating the regulation of processes like endoplasmic reticulum-associated degradation (ERAD), protein turnover, and ubiquitin-proteasome pathways UBXN11 also plays a role in autophagy by modulating protein extraction and lysosomal targeting during cellular stress Its involvement in maintaining proteostasis ensures the removal of misfolded or aggregated proteins, critical for cell survival Dysregulation of UBXN11 is linked to neurodegenerative diseases such as Alzheimer’s and Huntington’s, where defective protein clearance contributes to disease progression UBXN11 is also implicated in cancer biology, where its role in protein turnover and stress response can influence tumor growth, survival, and therapy resistance Emerging evidence highlights its potential function in cellular signaling pathways, particularly those associated with proteotoxic stress, autophagy, and DNA damage repair
Características del producto
category
ELISA Kits
immunogen target
UBX Domain-Containing Protein 11 (UBXN11)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
COA-1,PP2243,SOC,SOCI,UBXD5,Colorectal tumor-associated antigen,UBX domain-containing protein 5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
UBXN11
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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