Rat Ubiquitin Specific Peptidase 1 (USP1) Protein

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Description
Rat USP1 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Ubiquitin Specific Peptidase 1 (USP1) |
Host | E. coli |
Origin | Rat |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 26.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-His198 Tag: N-terminal His tag |
Expression | Recombinant |
Purity | > 90% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q569C3 |
Background | Protein USP1 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
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