USP1 antibody

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Description
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ubiquitin specific peptidase 1 (USP1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:200-1:2000; IHC: 1:20-1:200;IP: 1:200-1:1000 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 100 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IP |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O94782 |
Gene ID | 7398 |
Alias | Ubiquitin carboxyl-terminal hydrolase 1,Deubiquitinating enzyme 1 (hUBP),Ubiquitin thioesterase 1,Ubiquitin-specific-processing protease 1,Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment,USP1 |
Background | Antibody anti-USP1 |
Status | RUO |
Note | Mol. Weight 100 kDa |
Descripción
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Human USP1 (Ubiquitin carboxyl-terminal hydrolase 1) ELISA Kit
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USP1 antibody
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
Ver Producto
USP1 antibody
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2(PubMed:15694335). Also involved in PCNA-mediated translesion synthesis(TLS) by deubiquitinating monoubiquitinated PCNA(PubMed:16531995). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity(PubMed:18082604, PubMed:26388029).
Ver Producto