Rat Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein
1079€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693003
tested applications
SDS-PAGE
Description
Rat TNFRSF17 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat TNFRSF17 (D3ZKQ8) (Met1-Thr49) was expressed, fused with the Fc region of human IgG1 at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | TNFRSF17 |
| Host | HEK293 cells |
| Origin | Rat |
| Observed MW | Molecular Weight: 34 kDa Sequence Fragment: Met1-Thr49 Tag: N-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 99% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Tumor necrosis factor receptor superfamily member 17,BCM,BCMA,CD269,TNFRSF13A,B-cell maturation protein |
| Background | Protein TNFRSF17 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity. TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity.
Related Products
Human TNFRSF17 (Tumor necrosis factor receptor superfamily member 17) ELISA Kit
Ver Producto
Monkey TNFRSF17/BCMA (Tumor necrosis factor receptor superfamily member 17) ELISA Kit
Ver Producto