Mouse Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein

Name: Mouse Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17) Protein
Brand: Abbexa
SKU: abx069561
Price: 234 EUR
Availability: OnlineOnly

Este producto es parte de TNFRSF17 - TNF receptor superfamily member 17

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein TNFRSF17

proveedor

Abbexa

reference

abx069561

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Background

TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity. TNFRSF17, also known as B-cell maturation antigen (BCMA), is a receptor within the tumor necrosis factor receptor superfamily (TNFRSF). It is primarily expressed on B cells, specifically on mature and plasma B cells, where it plays a pivotal role in B cell survival, differentiation, and immunoglobulin secretion. TNFRSF17 is unique among TNFRSF members because of its specificity for binding ligands like APRIL (A Proliferation-Inducing Ligand) and BAFF (B-cell Activating Factor), which are members of the TNF ligand superfamily. BCMA is essential for maintaining long-lived plasma cells and for regulating immune responses, particularly in the context of adaptive immunity.

Características del producto

origin

Mouse

host

E. coli

immunogen target

Tumor Necrosis Factor Receptor Superfamily Member 17 (TNFRSF17)

host

E. coli

conjugation

Unconjugated

form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

500 µg

observerd MW

Molecular Weight: Calculated MW: 14.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu71-Thr184 Tag: N-terminal His tag

purity

> 95%

buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

TNFRSF17

dry ice

availability

Shipped within 5-12 working days.

alias

Tumor necrosis factor receptor superfamily member 17,BCM,BCMA,CD269,TNFRSF13A,B-cell maturation protein

uniprot id

https://www.uniprot.org/uniprotkb/O88472

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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proveedor

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reference

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reactivity

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status

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Precio a consultar

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proveedor

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reference

abx038171

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

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357.5€ (100 µg)