Rat Tnfrsf1a (Tumor necrosis factor receptor superfamily member 1A) ELISA Kit

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935106861
info@markelab.com
name
Rat Tnfrsf1a (Tumor necrosis factor receptor superfamily member 1A) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0129
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
15.625-1000pg/ml
Sensitivity
9.375pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P22934
Alias
FPF,p55,p60,TBP1,TNF-R,TNFAR,TNFR1,p55-R,CD120a,TNFR55,TNFR60,TNF-R-I,TNF-R55,Tumor necrosis factor receptor superfamily member 1A,Tumor necrosis factor receptor type I
Background
Elisa kits for Tnfrsf1a
Status
RUO

TNFRSF1A , also known as Tumor Necrosis Factor Receptor Superfamily Member 1A or TNFR1 , is a prominent cell surface receptor that binds tumor necrosis factor-alpha (TNF-α). TNFR1 plays a critical role in regulating immune responses, cell survival, apoptosis, and inflammation, making it an essential component in both innate and adaptive immunity. The TNFRSF1A gene is located on chromosome 12p13.31 and encodes a protein that is expressed in nearly all cell types, with high expression in immune cells, epithelial cells, and neurons. As a member of the TNF receptor superfamily, TNFRSF1A is involved in multiple signaling pathways, depending on cellular and environmental conditions. Upon binding to TNF-α, TNFR1 can trigger both pro-inflammatory responses and cell death pathways, depending on the context of signaling and additional molecules present. This receptor’s dual role is tightly regulated, as overactivation of TNFR1-mediated pathways can lead to pathological inflammation, while insufficient TNFR1 activity may hinder immune responses.

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