Rat TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) ELISA Kit

715€ (96 tests)
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935106861
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name
Rat TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx156166
tested applications
ELISA
Description
Rat TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Tumor Necrosis Factor Receptor Superfamily, Member 5 (TNFRSF5)
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | ELISA Kits |
Immunogen Target | TNF Receptor Superfamily Member 5 / TNFRSF5 (CD40) |
Reactivity | Rat |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 15.6 pg/ml - 1000 pg/ml |
Sensitivity | < 5.8 pg/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Serum, plasma and other biological fluids. |
Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
Alias | p50,Bp50,CDW40,TNFRSF5,Tumor necrosis factor receptor superfamily member 5,B-cell surface antigen CD40,CD40L receptor,CDw40,CD40 |
Background | Elisa kits for CD40 |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CD40 is a co-stimulatory protein primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells (DCs), macrophages, and certain types of endothelial cells. This molecule plays a critical role in both innate and adaptive immune responses. It is a member of the tumor necrosis factor receptor (TNFR) superfamily, specifically classified as TNFRSF5. CD40 is essential for initiating and sustaining immune responses, particularly by interacting with its ligand, CD40L (CD154), which is predominantly expressed on activated T cells. The CD40-CD40L interaction is a central element in immune regulation, providing necessary signals for B cell activation, differentiation, and class switching during antibody responses. Furthermore, CD40 signaling influences macrophage activation, dendritic cell maturation, and cytokine production, all of which are crucial for orchestrating immune responses.
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