Rat T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Protein (Active)

Este producto es parte de CD86 molecule
Rat T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Protein (Active)
1118€ (100 µg)

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Name
Rat T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Protein (Active)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx692047
Tested Applications
SDS-PAGE

Description

Rat CD86 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat CD86 (NP_064466.1) extracellular domain (Met 1-Ile 250) was expressed, fused with a polyhistidine tag at the C-terminus.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
CD86
Host
HEK293 cells
Assay Type
Activity: Active
Sequence Fragment: Met1-Ile250
Tag: C-terminal His tag
Origin
Rat
Observed MW
26.8 kDa
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
100 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
NCBI Accession
NP_064466.1
Alias
B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
Background
Protein CD86
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg of the protein as determined by the LAL method.

Background

CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.

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