Rat T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Protein (Active)
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935106861
info@markelab.com
Precio
871€ (100 µg)
Protein CD86
proveedor
Abbexareference
abx692047Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat CD86 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat CD86 (NP_064466.1) extracellular domain (Met 1-Ile 250) was expressed, fused with a polyhistidine tag at the C-terminus.
Background
CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.
Características del producto
category
Proteins and Peptides
origin
Rat
host
HEK293 cells
immunogen target
CD86
host
HEK293 cells
form
tested applications
SDS-PAGE
size 1
100 µg
observerd MW
Molecular Weight: 26.8 kDa Sequence Fragment: Met1-Ile250 Tag: C-terminal His tag Validity: The validity for this protein is 12 months.
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
Lyophilized from sterile PBS, pH 7.4.
storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
or code
CD86
dry ice
No
availability
Shipped within 5-15 working days.
alias
B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
NCBI accession
NP_064466.1
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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