Rat T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Protein

Este producto es parte de CD86 molecule
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247€ (10 µg)

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935106861
info@markelab.com
name
Rat T-Lymphocyte Activation Antigen CD86 / B7-2 (CD86) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690109
tested applications
SDS-PAGE

Description

Rat T-lymphocyte Activation Antigen CD86 Protein is a recombinant protein from Rat produced in Human cells. Recombinant Rat T-lymphocyte Activation Antigen CD86 is produced by our Mammalian expression system and the target gene encoding Vla29-Lys247 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
T-lymphocyte Activation Antigen CD86
Host
Human
Origin
Rat
Observed MW
Molecular Weight: 25.9 kDa
Sequence Fragment: Vla29-Lys247
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
PBS, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
O35531
Alias
B70,B7-2,B7.2,LAB72,CD28LG2,Activation B7-2 antigen,BU63,CTLA-4 counter-receptor B7.2,FUN-1,T-lymphocyte activation antigen CD86
Background
Protein CD86
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD86, also known as B7-2, is a transmembrane glycoprotein that plays a crucial role in the costimulatory signaling necessary for T-cell activation and immune response. It is a member of the immunoglobulin (Ig) superfamily and is encoded by the CD86 gene located on chromosome 3q21. CD86 is primarily expressed on antigen-presenting cells (APCs) such as dendritic cells, macrophages, and B cells. The interaction of CD86 with its receptors, CD28 and CTLA-4 (CD152), on T cells is vital for regulating immune responses, influencing both the activation and inhibition of T cells.

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