Rat T-lymphocyte activation antigen CD80 / B7-1 (CD80) Protein

Este producto es parte de CD80 molecule
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247€ (10 µg)

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935106861
info@markelab.com
name
Rat T-lymphocyte activation antigen CD80 / B7-1 (CD80) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx690106
tested applications
SDS-PAGE

Description

Rat T-lymphocyte Activation Antigen CD80 Protein is a recombinant protein from Rat produced in Human cells. Recombinant Rat T-lymphocyte Activation Antigen CD81 is produced by our Mammalian expression system and the target gene encoding Vla30-Gln248 is expressed with a 6His tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
T-lymphocyte Activation Antigen CD80
Host
Human
Origin
Rat
Observed MW
Molecular Weight: 25.7 kDa
Sequence Fragment: Vla30-Gln248
Tag: C-terminal 6 His tag
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
10 µg
Size 2
50 µg
Form
Lyophilized 
Tested Applications
SDS-PAGE
Buffer
PBS, pH7.4.
Availability
Shipped within 5-15 working days.
Storage
Store at < -20°C.
Dry Ice
No
UniProt ID
O35187
Alias
B7,BB1,B7-1,B7.1,LAB7,CD28LG,CD28LG1,Activation B7-1 antigen,CTLA-4 counter-receptor B7.1,T-lymphocyte activation antigen CD80
Background
Protein CD80
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD80, also known as B7-1, is a protein encoded by the CD80 gene in humans. It is an essential costimulatory molecule expressed on the surface of antigen-presenting cells (APCs) such as dendritic cells, B cells, and macrophages. CD80 plays a critical role in the regulation of immune responses by providing the necessary second signal for T cell activation and survival. This molecule interacts with CD28 and CTLA-4 receptors on T cells, mediating various immune responses. The discovery and understanding of CD80 have significant implications for immunology, particularly in the context of autoimmune diseases, transplant rejection, and cancer immunotherapy.

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