Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit

Este producto es parte de CD14 - Cluster of Differentiation 14
Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

546€ (96 tests)

Elisa kits for CD14

proveedor

Abbexa

reference

abx255986

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Soluble Cluster of Differentiation 14 (sCD14) concentrations in serum, plasma, tissue homogenates and other biological fluids.


Background

Soluble Cluster of Differentiation 14 (sCD14) is a crucial glycoprotein primarily expressed on the surface of monocytes, macrophages, and neutrophils, as well as existing in a soluble form (sCD14) in circulation. This molecule acts as a co-receptor for the detection of bacterial lipopolysaccharides (LPS), a component of Gram-negative bacterial cell walls, in conjunction with Toll-like receptor 4 (TLR4) and MD-2. CD14 is pivotal in innate immunity, where it aids in the recognition of pathogens and triggers immune responses. Soluble CD14 is particularly significant in tissues and cells lacking membrane-bound CD14, enabling a broader immune response. Dysregulation of CD14 levels is linked to various inflammatory and infectious diseases, including sepsis, atherosclerosis, and autoimmune conditions. As a biomarker, soluble CD14 is used in research and clinical diagnostics to assess inflammation and immune activation. It plays an essential role in understanding host-pathogen interactions and inflammatory pathways.

Características del producto

category

ELISA Kits


immunogen target

Soluble Cluster of Differentiation 14 (sCD14)


reactivity

Rat


test range

1.56 ng/ml - 100 ng/ml


sensitivity

0.94 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

sCD14|Soluble Cluster of Differentiation14|CD14|CD14 antigen|CD14 molecule|monocyte differentiation antigen CD14|Myeloid cell-specific leucine-rich glycoprotein


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

CD14


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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