Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit

585€ (96 tests)
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name
Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx255986
tested applications
ELISA
Description
Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Soluble Cluster of Differentiation 14 (sCD14) concentrations in serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Soluble Cluster of Differentiation 14 (sCD14) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 1.56 ng/ml - 100 ng/ml |
| Sensitivity | 0.94 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q63691 |
| Gene ID | 60350 |
| Alias | sCD14|Soluble Cluster of Differentiation14|CD14|CD14 antigen|CD14 molecule|monocyte differentiation antigen CD14|Myeloid cell-specific leucine-rich glycoprotein |
| Background | Elisa Kits for: CD14 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Soluble Cluster of Differentiation 14 (sCD14) is a crucial glycoprotein primarily expressed on the surface of monocytes, macrophages, and neutrophils, as well as existing in a soluble form (sCD14) in circulation. This molecule acts as a co-receptor for the detection of bacterial lipopolysaccharides (LPS), a component of Gram-negative bacterial cell walls, in conjunction with Toll-like receptor 4 (TLR4) and MD-2. CD14 is pivotal in innate immunity, where it aids in the recognition of pathogens and triggers immune responses. Soluble CD14 is particularly significant in tissues and cells lacking membrane-bound CD14, enabling a broader immune response. Dysregulation of CD14 levels is linked to various inflammatory and infectious diseases, including sepsis, atherosclerosis, and autoimmune conditions. As a biomarker, soluble CD14 is used in research and clinical diagnostics to assess inflammation and immune activation. It plays an essential role in understanding host-pathogen interactions and inflammatory pathways.
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