Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
546€ (96 tests)
Elisa kits for CD14
proveedor
Abbexareference
abx255986Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Soluble Cluster of Differentiation 14 (sCD14) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Soluble Cluster of Differentiation 14 (sCD14) concentrations in serum, plasma, tissue homogenates and other biological fluids.
Background
Soluble Cluster of Differentiation 14 (sCD14) is a crucial glycoprotein primarily expressed on the surface of monocytes, macrophages, and neutrophils, as well as existing in a soluble form (sCD14) in circulation. This molecule acts as a co-receptor for the detection of bacterial lipopolysaccharides (LPS), a component of Gram-negative bacterial cell walls, in conjunction with Toll-like receptor 4 (TLR4) and MD-2. CD14 is pivotal in innate immunity, where it aids in the recognition of pathogens and triggers immune responses. Soluble CD14 is particularly significant in tissues and cells lacking membrane-bound CD14, enabling a broader immune response. Dysregulation of CD14 levels is linked to various inflammatory and infectious diseases, including sepsis, atherosclerosis, and autoimmune conditions. As a biomarker, soluble CD14 is used in research and clinical diagnostics to assess inflammation and immune activation. It plays an essential role in understanding host-pathogen interactions and inflammatory pathways.
Características del producto
category
ELISA Kits
immunogen target
Soluble Cluster of Differentiation 14 (sCD14)
reactivity
Rat
test range
1.56 ng/ml - 100 ng/ml
sensitivity
0.94 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
sCD14|Soluble Cluster of Differentiation14|CD14|CD14 antigen|CD14 molecule|monocyte differentiation antigen CD14|Myeloid cell-specific leucine-rich glycoprotein
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD14
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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