Rat Ras-Related Protein Rab-7a (RAB7A) ELISA Kit
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Description
Rat Ras-Related Protein Rab-7a (RAB7A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Ras-Related Protein Rab-7a concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Ras-Related Protein Rab-7a (RAB7A) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.15 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P09527 |
| Alias | RAB7,CMT2B,PRO2706,Ras-related protein Rab-7a |
| Background | Elisa kits for RAB7A |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
RAB7A, member RAS oncogene family (RAB7A) is a GTPase that plays a central role in regulating late endosomal and lysosomal trafficking, which is crucial for maintaining cellular homeostasis and protein degradation RAB7A is involved in controlling the movement of vesicles from early endosomes to late endosomes and from late endosomes to lysosomes, where materials are processed and degraded It also regulates autophagy, a cellular process responsible for the recycling of damaged organelles and proteins RAB7A’s involvement in these pathways helps control cellular signaling, immune responses, and tissue homeostasis Additionally, RAB7A has been shown to play a role in regulating the transport of key receptors involved in cell survival and immune responses Mutations or dysregulation of RAB7A are linked to several diseases, including neurodegenerative disorders, where defective vesicular transport impairs the clearance of cellular waste and leads to the accumulation of toxic substances Understanding RAB7A’s role in vesicular trafficking is critical for developing potential therapies for neurodegenerative diseases and cancer, where altered cellular transport processes contribute to disease pathogenesis
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