Rat Ragulator Complex Protein LAMTOR3 / MAPKSP1 (LAMTOR3) ELISA Kit

715€ (96 tests)
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935106861
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name
Rat Ragulator Complex Protein LAMTOR3 / MAPKSP1 (LAMTOR3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx391623
tested applications
ELISA
Description
Rat Ragulator complex protein LAMTOR3 (LAMTOR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat LAMTOR3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Ragulator Complex Protein LAMTOR3 / MAPKSP1 (LAMTOR3) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q5U204 |
| Gene ID | 362045 |
| Alias | MAP2K1IP1,MAPBP,MAPKSP1,MP1,PRO0633,Ragulator3,Mitogen-activated protein kinase scaffold protein 1,late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
| Background | Elisa Kits for: LAMTOR3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Ragulator complex protein LAMTOR3 is an integral subunit of the lysosomal Ragulator complex that functions as a critical activator of the mTORC1 pathway in response to amino acid and nutrient signaling LAMTOR3 is required for the localization of Rag GTPases to the lysosomal surface, which facilitates the recruitment of mTORC1 and its activation upon nutrient availability Beyond its role in nutrient sensing, LAMTOR3 regulates lysosomal positioning and intracellular trafficking processes Dysregulation of LAMTOR3 disrupts mTOR signaling and has been linked to cellular growth defects, metabolic disorders, and tumor progression Studies highlight its role in maintaining energy balance and cell survival under stress conditions LAMTOR3 also participates in immune cell responses, as mTORC1 signaling is vital for T-cell activation and differentiation Its involvement in nutrient sensing and cellular homeostasis underscores its importance in both normal physiology and disease pathogenesis
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