Rat Ras-Related Protein Rab-21 (RAB21) ELISA Kit

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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Ras-Related Protein Rab-21 (RAB21) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx541100
tested applications
ELISA

Description

Rat Ras-Related Protein Rab-21 (RAB21) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Ras-Related Protein Rab-21 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Ras-Related Protein Rab-21 (RAB21)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.07 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6AXT5
Alias
KIAA0118,Ras-related protein Rab-21
Background
Elisa kits for RAB21
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB21, member RAS oncogene family (RAB21) is a small GTPase that regulates vesicle trafficking between endosomes and the plasma membrane, playing a crucial role in the recycling of cell surface receptors and other membrane proteins RAB21 is involved in processes such as integrin trafficking, which is essential for maintaining cell adhesion, migration, and the integrity of cell junctions It is particularly important in regulating the transport and recycling of receptors that control cellular signaling, helping to ensure proper receptor availability on the cell surface for growth factor signaling and immune response Additionally, RAB21 contributes to the regulation of cellular polarity and the organization of the actin cytoskeleton, which is essential for processes like cell migration and tissue remodeling RAB21’s dysfunction is linked to diseases such as cancer, where alterations in receptor trafficking and integrin function contribute to metastasis and tumor progression Moreover, RAB21 plays a role in immune function, where defects in vesicular trafficking can impact immune receptor trafficking, affecting immune responses and inflammation

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