Rat Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) ELISA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
Rat Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) ELISA Kit
715€ (96 tests)

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Name
Rat Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx540765
Tested Applications
ELISA

Description

Rat Protein Tyrosine Phosphatase, Receptor Type R (PTPRR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Receptor-type tyrosine-protein phosphatase R concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Protein Tyrosine Phosphatase, Receptor Type R (PTPRR)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
O08617
Alias
PTPRQ,EC-PTP,PCPTP1,PTP-SL,PTPBR7,Protein-tyrosine phosphatase PCPTP1,Ch-1PTPase,NC-PTPCOM1,R-PTP-R,Receptor-type tyrosine-protein phosphatase R
Background
Elisa Kits for: PTPRR
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

PTPRR is a receptor-type protein tyrosine phosphatase involved in regulating signal transduction pathways critical for neuronal function and development. Structurally, PTPRR contains a single transmembrane domain and an intracellular phosphatase domain. It is primarily expressed in the central nervous system (CNS), particularly in the brain and cerebellum. PTPRR is involved in modulating mitogen-activated protein kinase (MAPK) signaling by dephosphorylating and inactivating ERK1/2, thereby regulating neuronal differentiation, synaptic plasticity, and signal propagation. PTPRR isoforms differ in size and localization due to alternative splicing, including membrane-bound and cytosolic forms. Mutations or dysregulation of PTPRR have been associated with neurological disorders such as ataxia and cognitive deficits. PTPRR also participates in cellular responses to external stimuli by modulating kinase activity. Its regulatory role in neuronal signaling underscores its importance in brain development, synaptic transmission, and neurodegenerative disease processes.

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