Rat Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx540738
tested applications
ELISA
Description
Rat Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Receptor-type tyrosine-protein phosphatase N2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein Tyrosine Phosphatase Receptor Type N2 (PTPRN2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q63475 |
| Alias | IAR,ICAAR,PTPRP,IA-2beta,R-PTP-N2,Phogrin,Islet cell autoantigen-related protein,Receptor-type tyrosine-protein phosphatase N2 |
| Background | Elisa kits for PTPRN2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRN2, also known as IA-2β or phogrin, is closely related to PTPRN and is predominantly expressed in neuroendocrine and neuronal tissues. Like PTPRN, PTPRN2 has a transmembrane region and an intracellular domain with a catalytically inactive phosphatase-like region. PTPRN2 plays a crucial role in insulin and neurotransmitter secretion by regulating secretory granule biogenesis, transport, and exocytosis. It is particularly involved in maintaining the structural integrity of granules and their exocytotic machinery. PTPRN2 is an autoantigen in type 1 diabetes, contributing to β-cell autoimmunity and destruction. It has also been implicated in neurological functions, including synaptic vesicle release and neurotransmitter regulation. Dysregulation of PTPRN2 has been associated with metabolic diseases and neuropsychiatric disorders, highlighting its significance in endocrine and neuronal cell function.
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