Rat Protein C Receptor, Endothelial (PROCR) CLIA Kit
643.5€ (96 tests)
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name
Rat Protein C Receptor, Endothelial (PROCR) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196195
tested applications
CLIA
Description
Rat Endothelial Protein C Receptor (EPCR) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Endothelial Protein C Receptor (EPCR).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Protein C Receptor, Endothelial (PROCR) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CCCA,EPCR,CCD41,Endothelial protein C receptor, Activated protein C receptor,APC receptor,Endothelial cell protein C receptor |
| Background | CLIA Kits PROCR |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PROCR, also known as the endothelial protein C receptor (EPCR), is a critical component of the protein C anticoagulant pathway. This pathway has essential roles in regulating blood coagulation, inflammation, and maintaining vascular integrity. PROCR is primarily expressed on endothelial cells lining blood vessels and binds to activated protein C (APC) to enhance its anticoagulant effects. This interaction is vital for limiting thrombosis, mitigating inflammation, and preserving the barrier function of blood vessels, especially in response to inflammatory and coagulatory challenges. Recent research has revealed additional roles for PROCR, including functions in immune response modulation, cell proliferation, and tissue regeneration.
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PROCR Antibody is a Rabbit Polyclonal antibody against PROCR. The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
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