Rat Prostaglandin E Receptor 4 (PTGER4) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Prostaglandin E Receptor 4 (PTGER4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx538351
tested applications
ELISA
Description
Rat Prostaglandin E Receptor 4 (PTGER4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Prostaglandin E2 receptor EP4 subtype concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Prostaglandin E Receptor 4 (PTGER4) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P43114 |
| Alias | PTGER4,EP2,PGE receptor EP4 subtype,prostanoid EP4 receptor,EP4R |
| Background | Elisa kits for PTGER4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTGER4, or EP4, is a G protein-coupled receptor activated by prostaglandin E2 (PGE2), playing a key role in inflammation, immune regulation, and tissue homeostasis. EP4 primarily couples to Gs proteins, stimulating adenylate cyclase, increasing cAMP levels, and activating downstream signaling pathways such as PKA, PI3K/Akt, and β-arrestin. EP4 is widely expressed in immune cells, endothelial cells, and epithelial tissues, where it mediates vasodilation, bone remodeling, and anti-inflammatory effects. In the immune system, EP4 regulates T cell differentiation, macrophage activity, and cytokine production, contributing to inflammation resolution. Dysregulation of EP4 signaling is implicated in chronic inflammatory diseases, autoimmune disorders, and cancer, where EP4 activation promotes angiogenesis, immune evasion, and tumor growth. EP4 agonists are being investigated for conditions like osteoarthritis and ulcerative colitis due to their anti-inflammatory effects, while EP4 antagonists are explored for cancer therapy and cardiovascular diseases, where modulation of PGE2 responses holds therapeutic potential.
Related Products
PTGER4 antibody
Ver Producto
Prostaglandin E Receptor 4 (PTGER4) Antibody
Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G (s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Ver Producto
Prostaglandin E Receptor 4 (PTGER4) Antibody
PTGER4 Antibody is a Rabbit Polyclonal against PTGER4.
Ver Producto