Rat Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B) Protein

Este producto es parte de ALOX - Arachidonate lipoxygenase
Rat Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein ALOX15B

proveedor

Abbexa

reference

abx167673

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Arachidonate-15-Lipoxygenase, Type B Protein is a recombinant Rat protein expressed in E. coli.


Background

ALOX15B, a close homolog of ALOX15, catalyzes the formation of 15(S)-HETE from arachidonic acid and other polyunsaturated fatty acids. Unlike ALOX15, ALOX15B is highly expressed in epithelial tissues, including the prostate, lung, and skin, where it plays a role in maintaining cellular homeostasis, inflammation resolution, and lipid metabolism. ALOX15B-derived lipid mediators regulate anti-inflammatory responses and oxidative stress, contributing to tissue repair and barrier function. Its dysregulation has been implicated in prostate cancer, where altered ALOX15B expression promotes cell proliferation, survival, and tumor progression through lipid signaling pathways. In addition, ALOX15B has a role in metabolic diseases, such as obesity and diabetes, where it influences lipid signaling and insulin sensitivity. ALOX15B’s ability to modulate inflammatory pathways and lipid homeostasis makes it a potential therapeutic target for cancer, metabolic disorders, and inflammatory diseases.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 35.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp349-Val633 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ALOX15B


dry ice

No


availability

Shipped within 5-7 working days.


alias

15-lipoxygenase 2,Arachidonate 15-lipoxygenase B


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

Human ALOX15B(Arachidonate 15-lipoxygenase B) ELISA Kit

Human ALOX15B(Arachidonate 15-lipoxygenase B) ELISA Kit

proveedor

FineTest

reference

EH1526

reactivity

human

status

RUO

Precio a consultar

Ver más

Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B) Antibody

Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B) Antibody

proveedor

Abbexa

reference

abx005232

Tested Applications

WB, IF/ICC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

ALOX15B Antibody is a Rabbit Polyclonal antibody against ALOX15B. This gene encodes a member of the lipoxygenase family ...

312€ (60 µl)

Ver más

Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B) Antibody

Polyunsaturated Fatty Acid Lipoxygenase ALOX15B (ALOX15B) Antibody

proveedor

Abbexa

reference

abx034274

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the pr...

292.5€ (80 µl)

Ver más