Rat PLAUR/uPAR (Urokinase plasminogen activator surface receptor) ELISA Kit

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935106861
info@markelab.com
name
Rat PLAUR/uPAR (Urokinase plasminogen activator surface receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0184
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
78.125-5000pg/ml
Sensitivity
46.875pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P49616
Alias
CD87,UPAR,URKR,U-PAR,Urokinase plasminogen activator surface receptor,Monocyte activation antigen Mo3
Background
Elisa kits for Plaur
Status
RUO

The plasminogen activator, urokinase receptor (PLAUR), also known as urokinase plasminogen activator receptor (uPAR), is a cell surface receptor that plays a pivotal role in modulating extracellular matrix degradation, cell adhesion, and migration. PLAUR is mainly expressed on various cell types, including immune cells (like monocytes and neutrophils), endothelial cells, and cancer cells, and it orchestrates processes crucial for tissue remodeling, inflammation, and metastasis. PLAUR facilitates these processes by binding to urokinase-type plasminogen activator (uPA) and concentrating proteolytic activity on the cell surface, contributing to localized extracellular proteolysis and influencing signal transduction pathways that mediate cell movement and adhesion. This receptor is encoded by the PLAUR gene, located on chromosome 19q13, and belongs to the Ly6/uPAR/α-neurotoxin receptor family, a superfamily of proteins involved in signal transduction.

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