Rat Platelet Derived Growth Factor Receptor Alpha (PDGFRA) ELISA Kit

Este producto es parte de PDGFR - platelet derived growth factor receptor
Rat Platelet Derived Growth Factor Receptor Alpha (PDGFRA) ELISA Kit

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935106861

info@markelab.com

Precio

531.25€ (96 tests)

Elisa Kits PDGFRA

proveedor

Abbexa

reference

abx255911

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Platelet Derived Growth Factor Receptor Alpha (PDGFRA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Platelet Derived Growth Factor Receptor Alpha (PDGFRA) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Platelet derived growth factor receptor alpha (PDGFRA) is a tyrosine kinase receptor that binds specifically to platelet-derived growth factors (PDGFs), initiating intracellular signaling cascades that regulate cell proliferation, differentiation, and migration in a variety of tissues during development and wound healing it is predominantly expressed in mesenchymal cells and plays a key role in the development of the cardiovascular system, smooth muscle cells, and connective tissue its activation promotes pathways like the MAPK and PI3K-AKT signaling axes, which are critical for cellular responses such as survival and proliferation mutations or overexpression of PDGFRA are frequently associated with oncogenesis in gastrointestinal stromal tumors (GISTs) and other cancers making it a target for tyrosine kinase inhibitors like imatinib further studies are exploring its role in tissue repair and fibrosis, revealing its potential in therapeutic interventions for chronic inflammatory and fibrotic diseases.

Características del producto

category

ELISA Kits


immunogen target

Platelet Derived Growth Factor Receptor Alpha (PDGFRA)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

0.1 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

CD140A,PDGFR2,PDGFR-2,Platelet-derived growth factor receptor 2,Alpha platelet-derived growth factor receptor,Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

PDGFRA


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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