Rat Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits PTPRQ
proveedor
Abbexareference
abx514796Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Phosphotidylinositol phosphatase PTPRQ (PTPRQ) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Phosphotidylinositol phosphatase PTPRQ concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRQ is a receptor-like protein tyrosine phosphatase that plays critical roles in hair cell function, auditory processes, and cellular signaling. Structurally, PTPRQ contains extracellular domains, a single transmembrane region, and an intracellular phosphatase domain with enzymatic activity. It is primarily expressed in sensory hair cells of the inner ear, where it regulates the structure and function of stereocilia, specialized actin-rich projections responsible for mechanotransduction. PTPRQ is essential for maintaining hair cell integrity and hearing function by modulating phosphatidylinositol signaling and dephosphorylating key targets. Mutations in PTPRQ are associated with autosomal recessive non-syndromic hearing loss, underscoring its importance in auditory physiology. Beyond the ear, PTPRQ also contributes to cellular adhesion, signaling, and cytoskeletal dynamics. Its dysfunction highlights its role in sensory processes and cellular regulation.
Características del producto
category
ELISA Kits
immunogen target
Phosphotidylinositol phosphatase PTPRQ (PTPRQ)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.16 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
DFNA73,DFNB84,DFNB84A,PTPGMC1,R-PTP-Q,Receptor-type tyrosine-protein phosphatase Q,Phosphatidylinositol phosphatase PTPRQ
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRQ
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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