Rat PHD Finger Protein 5A (PHF5A) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PHF5A
proveedor
Abbexareference
abx538669Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat PHD Finger Protein 5A (PHF5A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat PHD finger-like domain-containing protein 5A concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PHF5A is a chromatin-binding protein that interacts with histones through its PHD finger domain and serves as a core component of the spliceosome complex. It regulates alternative splicing of pre-mRNA, controlling the expression of genes involved in cell cycle progression, differentiation, and apoptosis. PHF5A is essential for the recognition of splice sites and the recruitment of splicing machinery during transcription. It is ubiquitously expressed in proliferating tissues, particularly in stem cells and cancer cells, where it maintains proper gene expression programs. Dysregulation of PHF5A has been implicated in cancer, including glioblastoma and leukemia, where it promotes tumor progression by modulating splicing events that regulate survival and proliferation. Knockdown studies reveal impaired splicing, reduced cell proliferation, and increased apoptosis, underscoring its role as a critical regulator of RNA processing, transcription, and cellular growth.
Características del producto
category
ELISA Kits
immunogen target
PHD Finger Protein 5A (PHF5A)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
NI, Rds3, SAP14b, SF3B7, SF3b14b, bK223H9.2,PHD finger-like domain protein 5A
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PHF5A
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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