Rat Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) CLIA Kit

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935106861
info@markelab.com
Precio
845€ (96 tests)
CLIA Kits PPARGC1A
proveedor
Abbexareference
abx496609Tested Applications
CLIAreactivity
Ratstatus
RUOclonality
Descripción
Rat Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Background
PPARGC1A, also known as PGC-1α (Peroxisome proliferator-activated receptor gamma coactivator 1-alpha), is a transcriptional coactivator that plays a central role in the regulation of cellular energy metabolism and mitochondrial biogenesis. PPARGC1A interacts with and coactivates various transcription factors, including peroxisome proliferator-activated receptor gamma (PPARG) and nuclear respiratory factors (NRFs), to regulate the expression of genes involved in energy metabolism, oxidative phosphorylation, and mitochondrial function. It promotes the transcription of genes involved in fatty acid oxidation, glucose metabolism, and thermogenesis, thereby enhancing cellular energy production and expenditure. PPARGC1A is a master regulator of mitochondrial biogenesis, the process by which new mitochondria are formed. It stimulates the expression of nuclear-encoded mitochondrial genes and activates signaling pathways involved in mitochondrial biogenesis, such as the PPAR signaling pathway and the AMP-activated protein kinase (AMPK) pathway. Increased PPARGC1A activity leads to the proliferation and remodeling of mitochondria, resulting in enhanced cellular energy capacity and metabolic efficiency.
Características del producto
category
CLIA Kits
immunogen target
Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.127 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
LEM6,PGC1,PGC1A,PGC-1v,PPARGC1,PGC-1alpha,PGC-1(alpha)
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PPARGC1A
dry ice
No
uniprot id
note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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