Rat Pentraxin 3 (PTX3) Protein

Este producto es parte de PTX3 - Pentraxin 3
Rat Pentraxin 3 (PTX3) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein PTX3

proveedor

Abbexa

reference

abx068441

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Pentraxin 3 is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

PTX3 is a long pentraxin and key component of the innate immune system involved in recognizing pathogens, regulating inflammation, and facilitating tissue repair PTX3 is produced by various cell types, including macrophages, neutrophils, and endothelial cells, in response to inflammatory stimuli such as IL-1β, TNF-α, and Toll-like receptor activation It acts as a soluble pattern recognition receptor (PRR), binding microbial components, such as fungal conidia, and activating complement pathways to enhance pathogen clearance PTX3 also regulates angiogenesis and extracellular matrix remodeling during tissue repair Elevated PTX3 levels are observed in conditions like sepsis, cardiovascular disease, and autoimmune disorders, where it acts as a biomarker for inflammation and disease progression PTX3 plays protective roles in infections, while dysregulated expression contributes to chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis, where it modulates both innate and adaptive immunity

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Pentraxin 3 (PTX3)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 24.0 kDa Observed MW (SDS-PAGE): 26 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser195-Ser381 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

PTX3


dry ice

No


availability

Shipped within 5-7 working days.


alias

TSG-14,TNFAIP5,Pentaxin-related protein PTX3,Tumor necrosis factor alpha-induced protein 5,TNF alpha-induced protein 5


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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