Rat Parathyroid Hormone Receptor 2 (PTH2R) CLIA Kit
Pida mas información
935106861
info@markelab.com
Precio
618.75€ (96 tests)
CLIA Kits PTH2R
proveedor
Abbexareference
abx197408Tested Applications
CLIAreactivity
Ratstatus
RUOclonality
Descripción
Rat Parathyroid Hormone Receptor 2 (PTHR2) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Parathyroid Hormone Receptor 2 (PTHR2).
Rat Parathyroid Hormone Receptor 2 (PTHR2) CLIA Kit es un kit CLIA para la detección del Receptor 2 de la Hormona Paratiroidea (PTHR2) en ratas.
Background
PTH2R is a G protein-coupled receptor activated primarily by tuberoinfundibular peptide of 39 residues (TIP39) and, to a lesser extent, parathyroid hormone (PTH). Unlike PTH1R, PTH2R is not involved in calcium homeostasis but instead regulates neuroendocrine functions, pain signaling, and vasodilation. PTH2R is predominantly expressed in the central nervous system, including the hypothalamus and brainstem, as well as in pancreatic and cardiovascular tissues. It couples to Gs proteins, stimulating adenylate cyclase and increasing intracellular cAMP levels. PTH2R modulates neuropeptide release, pain perception, and stress responses. Emerging evidence suggests its involvement in regulating hypothalamic-pituitary functions and modulating blood flow. Dysregulation of PTH2R signaling is linked to altered pain sensitivity, stress-related disorders, and neuroendocrine dysfunction. Targeting PTH2R has therapeutic potential for managing chronic pain, stress disorders, and cardiovascular regulation, highlighting its role in neuropeptide-mediated signaling.
Características del producto
category
CLIA Kits
immunogen target
Parathyroid Hormone Receptor 2 (PTH2R)
reactivity
Rat
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
9.38 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
PTH2R,PTHR2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTH2R
dry ice
No
note
El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.
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