Rat Parathyroid Hormone Receptor 2 (PTH2R) CLIA Kit

Este producto es parte de PTHR - Parathyroid Hormone Receptor
Rat Parathyroid Hormone Receptor 2 (PTH2R) CLIA Kit

Pida mas información

935106861

info@markelab.com

Precio

618.75€ (96 tests)

CLIA Kits PTH2R

proveedor

Abbexa

reference

abx197408

Tested Applications

CLIA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Parathyroid Hormone Receptor 2 (PTHR2) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Parathyroid Hormone Receptor 2 (PTHR2).


Rat Parathyroid Hormone Receptor 2 (PTHR2) CLIA Kit es un kit CLIA para la detección del Receptor 2 de la Hormona Paratiroidea (PTHR2) en ratas.


Background

PTH2R is a G protein-coupled receptor activated primarily by tuberoinfundibular peptide of 39 residues (TIP39) and, to a lesser extent, parathyroid hormone (PTH). Unlike PTH1R, PTH2R is not involved in calcium homeostasis but instead regulates neuroendocrine functions, pain signaling, and vasodilation. PTH2R is predominantly expressed in the central nervous system, including the hypothalamus and brainstem, as well as in pancreatic and cardiovascular tissues. It couples to Gs proteins, stimulating adenylate cyclase and increasing intracellular cAMP levels. PTH2R modulates neuropeptide release, pain perception, and stress responses. Emerging evidence suggests its involvement in regulating hypothalamic-pituitary functions and modulating blood flow. Dysregulation of PTH2R signaling is linked to altered pain sensitivity, stress-related disorders, and neuroendocrine dysfunction. Targeting PTH2R has therapeutic potential for managing chronic pain, stress disorders, and cardiovascular regulation, highlighting its role in neuropeptide-mediated signaling.

Características del producto

category

CLIA Kits


immunogen target

Parathyroid Hormone Receptor 2 (PTH2R)


reactivity

Rat


test range

15.6 pg/ml - 1000 pg/ml


sensitivity

9.38 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Chemiluminescent


sample type

Serum, plasma and other biological fluids.


size 1

96 tests


alias

PTH2R,PTHR2 


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

PTH2R


dry ice

No


note

El rango y la sensibilidad pueden variar. Le recomendamos contactar con nosotros a fin de obtener la última información sobre posibles actualizaciones, que no estén representadas en este catalogo. Si necesita un rango específico, contáctenos y trataremos de ayudarle. Consulte sobre posible información que pueda ayudarle a elegir la dilución apropiada para sus muestras. Los kits CLIA están optimizados para la detección de muestras nativas, las proteínas recombinantes, pueden resultar problemáticas a causa de diferencias en la secuencia o cambios en la estructura terciaria.


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Tested Applications

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reference

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