Rat Oxytocin Receptor (OXTR) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Oxytocin Receptor (OXTR) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168509
tested applications
WB, SDS-PAGE
Description
Rat Oxytocin Receptor Protein is a recombinant Rat protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Oxytocin Receptor (OXTR) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Val43-Leu129 Tag: N-terminal His tag and GST tag |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 39.9 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | OXTR,OTR,OT-R |
| Background | Protein OXTR |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
OXTR is a G protein-coupled receptor activated by the hormone oxytocin, which plays a central role in childbirth, lactation, and social bonding. OXTR is expressed in various tissues, including the uterus, mammary glands, brain, and heart. In the uterus, oxytocin binds to OXTR to stimulate labor by causing uterine smooth muscle contraction. In lactating women, oxytocin binds to OXTR to facilitate milk ejection. OXTR in the brain is involved in promoting social bonding, maternal behaviors, and emotional responses, and has been implicated in the regulation of anxiety and stress. Dysregulation of OXTR signaling is associated with conditions such as autism spectrum disorder (ASD), where social bonding and empathy are impaired, and postpartum depression, where oxytocin signaling is thought to be altered. Research into OXTR agonists and antagonists holds promise for treating mood disorders, social dysfunction, and enhancing social bonding and attachment.
Related Products
Rat OXTR (Oxytocin receptor) ELISA Kit
Ver Producto
OXTR antibody
Oxytocin(OXT) is a neurohypophysial hormone that plays a role in lactation and parturition and in the central nervous system as a neurotransmitter involved in sex and maternal behavior(PMID: 1852313; 10811917). Oxytocin acts through its receptor, OXTR, which belongs to the G protein-coupled 7-transmembrane receptor family. OXTR is expressed in endometrium, myometrium, mammary gland(PMID: 1313946). This antibody is raised against the C-terminal region of human OXTR.
Ver Producto
Human Oxytocin Receptor (OXTR) Protein
Human Oxytocin Receptor (OXTR) is a recombinant Human protein expressed in E. coli.
Ver Producto