Human Oxytocin Receptor (OXTR) Protein

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935106861
info@markelab.com
Precio
221€ (10 µg)
Protein OXTR
proveedor
Abbexareference
abx068412Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Oxytocin Receptor (OXTR) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
OXTR is a G protein-coupled receptor activated by the hormone oxytocin, which plays a central role in childbirth, lactation, and social bonding. OXTR is expressed in various tissues, including the uterus, mammary glands, brain, and heart. In the uterus, oxytocin binds to OXTR to stimulate labor by causing uterine smooth muscle contraction. In lactating women, oxytocin binds to OXTR to facilitate milk ejection. OXTR in the brain is involved in promoting social bonding, maternal behaviors, and emotional responses, and has been implicated in the regulation of anxiety and stress. Dysregulation of OXTR signaling is associated with conditions such as autism spectrum disorder (ASD), where social bonding and empathy are impaired, and postpartum depression, where oxytocin signaling is thought to be altered. Research into OXTR agonists and antagonists holds promise for treating mood disorders, social dysfunction, and enhancing social bonding and attachment.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Oxytocin Receptor (OXTR)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 42.1 kDa Observed MW (SDS-PAGE): 42 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg272-Ser377 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
OXTR
dry ice
No
availability
Shipped within 5-7 working days.
alias
OXTR,OTR,OT-R
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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
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Abbexareference
abx068412Tested Applications
WB, SDS-PAGEstatus
RUORecombinant Oxytocin Receptor (OXTR) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli...
221€ (10 µg)
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