Human Oxytocin Receptor (OXTR) Protein

Este producto es parte de OXTR - Oxytocin Receptor
Human Oxytocin Receptor (OXTR) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein OXTR

proveedor

Abbexa

reference

abx068412

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Oxytocin Receptor (OXTR) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

OXTR is a G protein-coupled receptor activated by the hormone oxytocin, which plays a central role in childbirth, lactation, and social bonding. OXTR is expressed in various tissues, including the uterus, mammary glands, brain, and heart. In the uterus, oxytocin binds to OXTR to stimulate labor by causing uterine smooth muscle contraction. In lactating women, oxytocin binds to OXTR to facilitate milk ejection. OXTR in the brain is involved in promoting social bonding, maternal behaviors, and emotional responses, and has been implicated in the regulation of anxiety and stress. Dysregulation of OXTR signaling is associated with conditions such as autism spectrum disorder (ASD), where social bonding and empathy are impaired, and postpartum depression, where oxytocin signaling is thought to be altered. Research into OXTR agonists and antagonists holds promise for treating mood disorders, social dysfunction, and enhancing social bonding and attachment.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Oxytocin Receptor (OXTR)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 42.1 kDa Observed MW (SDS-PAGE): 42 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg272-Ser377 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

OXTR


dry ice

No


availability

Shipped within 5-7 working days.


alias

OXTR,OTR,OT-R


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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Human Oxytocin Receptor (OXTR) Protein

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proveedor

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reference

abx068412

Tested Applications

WB, SDS-PAGE

status

RUO

Recombinant Oxytocin Receptor (OXTR) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli...

221€ (10 µg)

Ver más