Rat Nucleoporin 88 (NUP88) ELISA Kit
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Description
Rat Nucleoporin 88 (NUP88) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Nuclear pore complex protein Nup88 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nucleoporin 88 (NUP88) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O08658 |
| Alias | nucleoporin 88kD,FADS4,Nuclear pore complex protein Nup88 |
| Background | Elisa kits for NUP88 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nucleoporin 88 (NUP88) is a component of the nuclear pore complex that plays a crucial role in regulating nucleocytoplasmic transport, particularly in the selective exchange of proteins, RNA, and other macromolecules between the nucleus and cytoplasm NUP88 contributes to the structural integrity of the nuclear pore and the transport processes that occur through it It is involved in facilitating the export of RNA from the nucleus and the import of various proteins that are essential for cellular functions such as gene expression, cell cycle regulation, and DNA repair NUP88 also interacts with other nucleoporins to form a part of the nuclear pore's central channel, which is critical for maintaining proper cellular function Studies have linked dysregulation of NUP88 to several diseases, particularly cancers, where its overexpression can promote tumor cell survival, metastasis, and resistance to chemotherapy Additionally, mutations in NUP88 are associated with altered protein trafficking and gene expression regulation, contributing to the pathogenesis of various disorders
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