Human Nucleoporin 88 kDa (NUP88) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein NUP88
proveedor
Abbexareference
abx068366Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Nucleoporin 88 kDa (NUP88) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Background
Nucleoporin 88 (NUP88) is a component of the nuclear pore complex that plays a crucial role in regulating nucleocytoplasmic transport, particularly in the selective exchange of proteins, RNA, and other macromolecules between the nucleus and cytoplasm NUP88 contributes to the structural integrity of the nuclear pore and the transport processes that occur through it It is involved in facilitating the export of RNA from the nucleus and the import of various proteins that are essential for cellular functions such as gene expression, cell cycle regulation, and DNA repair NUP88 also interacts with other nucleoporins to form a part of the nuclear pore's central channel, which is critical for maintaining proper cellular function Studies have linked dysregulation of NUP88 to several diseases, particularly cancers, where its overexpression can promote tumor cell survival, metastasis, and resistance to chemotherapy Additionally, mutations in NUP88 are associated with altered protein trafficking and gene expression regulation, contributing to the pathogenesis of various disorders
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Nucleoporin 88kDa (NUP88)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 31.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu476-Cys713 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NUP88
dry ice
No
availability
Shipped within 5-7 working days.
alias
nucleoporin 88kD,FADS4,Nuclear pore complex protein Nup88
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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