Rat Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Protein (Active)
1118€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Rat Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Protein (Active)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx692062
Tested Applications
SDS-PAGE
Description
Rat TrkA Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat NTRK1 (Met1-Pro418) was expressed with a polyhistidine tag at the C-terminus.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | TrkA |
| Host | HEK293 cells |
| Assay Type | Activity: Active Sequence Fragment: Met1-Pro418 Tag: C-terminal His tag |
| Origin | Rat |
| Observed MW | 43.7 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_067600.1 |
| Alias | MTC,TRK,TRK1,TRKA,rk-A,p140-TrkA,Tyrosine kinase receptor A,TRK1-transforming tyrosine kinase protein,Neurotrophic tyrosine kinase receptor type 1,High affinity nerve growth factor receptor |
| Background | Protein NTRK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg of the protein as determined by the LAL method. |
Background
Neurotrophic receptor tyrosine kinase 1 (NTRK1) is an essential receptor that binds with nerve growth factor (NGF), initiating critical signaling cascades required for the survival, differentiation, and functional maintenance of neurons, particularly within the peripheral nervous system. Beyond supporting neuronal growth, NTRK1 contributes to injury responses, helping facilitate neuronal repair and regeneration. Dysregulation or mutations in NTRK1 have been implicated in neurodegenerative diseases, such as Charcot-Marie-Tooth disease, as well as in certain cancers, making it a significant target for therapeutic research and drug development efforts.
Productos relacionados
Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Antibody
NTRK1 Antibody is a Rabbit Polyclonal antibody against NTRK1. This gene encodes a member of the neurotrophic tyrosine ki…
Ver producto
Tropomyosin Receptor Kinase A Phospho-Tyr791 (TrkA pY791) Antibody
Rabbit polyclonal antibody against Trk A protein. Immunogen region is C-terminal. Specificity is as follows for the reac…
Ver producto
Tropomyosin Receptor Kinase A Phospho-Tyr757 (TrkA pY757) Antibody
Rabbit polyclonal antibody against Trk A protein. Immunogen region is C-terminal. Specificity is as follows for the reac…
Ver producto