Rat Neurotrophic Receptor Tyrosine Kinase 1 (NTRK1) Protein
Pida mas información
935106861
info@markelab.com
Precio
837.5€ (100 µg)
Protein NTRK1
proveedor
Abbexareference
abx691153Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat TrkA Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat NTRK1 (P35739-Isoform TrkA-II)(Met1-Pro418) was expressed with the Fc region of human IgG1 at the C-terminus.
Background
Neurotrophic receptor tyrosine kinase 1 (NTRK1) is an essential receptor that binds with nerve growth factor (NGF), initiating critical signaling cascades required for the survival, differentiation, and functional maintenance of neurons, particularly within the peripheral nervous system. Beyond supporting neuronal growth, NTRK1 contributes to injury responses, helping facilitate neuronal repair and regeneration. Dysregulation or mutations in NTRK1 have been implicated in neurodegenerative diseases, such as Charcot-Marie-Tooth disease, as well as in certain cancers, making it a significant target for therapeutic research and drug development efforts.
Características del producto
category
Proteins and Peptides
origin
Rat
host
HEK293 cells
immunogen target
TrkA
host
HEK293 cells
tested applications
SDS-PAGE
size 1
100 µg
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
Lyophilized from sterile PBS, pH 7.4.
storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
or code
NTRK1
dry ice
No
availability
Shipped within 5-15 working days.
alias
MTC,TRK,TRK1,TRKA,rk-A,p140-TrkA,Tyrosine kinase receptor A,TRK1-transforming tyrosine kinase protein,Neurotrophic tyrosine kinase receptor type 1,High affinity nerve growth factor receptor
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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