Rat Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Rat Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx391770
tested applications
ELISA
Description
Rat Neuropeptide Y Receptor Y4 (NPY4R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat NPY4R concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Neuropeptide Y Receptor Y4 (NPY4R) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q63447 |
| Gene ID | 29471 |
| Alias | NPY4R,NPY4-R,PP1,PPYR1,Y4,PP1,neuropeptide Y receptor type 4,pancreatic polypeptide receptor 1 |
| Background | Elisa kits for NPY4R |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
NPY4R, also known as the pancreatic polypeptide receptor, is a G protein-coupled receptor activated primarily by pancreatic polypeptide (PP) and, to a lesser extent, by peptide YY (PYY) and neuropeptide Y (NPY). NPY4R is expressed in the hypothalamus, brainstem, and peripheral tissues, particularly in the gastrointestinal tract, pancreas, and adipose tissue. Activation of NPY4R regulates appetite, energy balance, and gastrointestinal function. It couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating neurotransmission. NPY4R plays a role in reducing food intake and regulating satiety, particularly following meal ingestion. Dysregulation of NPY4R is associated with obesity, metabolic disorders, and impaired pancreatic function. NPY4R agonists are being explored as therapeutic agents for obesity and type 2 diabetes, as enhancing NPY4R signaling can reduce appetite and improve glucose homeostasis. Its role in energy balance and metabolism highlights NPY4R as a promising target for managing obesity and metabolic diseases.
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