Rat Neuropeptide Y Receptor Y1 (NPY1R) CLIA Kit
845€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Neuropeptide Y Receptor Y1 (NPY1R) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx495079
tested applications
CLIA
Description
Rat Neuropeptide Y Receptor Y1 (NPY1R) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Neuropeptide Y Receptor Y1 (NPY1R) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.128 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P21555 |
| Gene ID | 29358 |
| Alias | NPY1R,NPY1-R,NPYR,NPY-Y1 receptor,FC5,neuropeptide Y receptor type 1,Y1-R |
| Background | CLIA Kits NPY1R |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
NPY1R is a G protein-coupled receptor activated by neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). It is predominantly expressed in the central nervous system (CNS), particularly in the hypothalamus, as well as peripheral tissues, where it regulates appetite, energy homeostasis, and cardiovascular function. NPY1R couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating calcium and potassium channels. Activation of NPY1R stimulates feeding behavior and reduces energy expenditure, contributing to weight gain and energy conservation. NPY1R is also involved in regulating stress responses, anxiety, and blood pressure. Dysregulation of NPY1R signaling is linked to obesity, metabolic disorders, and cardiovascular dysfunction. NPY1R antagonists are being explored as potential therapeutics for obesity and metabolic syndrome, as blocking NPY1R can reduce food intake and promote weight loss. Additionally, NPY1R modulators are being investigated for anxiety and stress-related conditions due to its role in emotional regulation.
Related Products
Human NPYR1 (Neuropeptide Y Receptor Y1) ELISA Kit
Ver Producto
Neuropeptide Y Receptor Y1 (NPY1R) Antibody
Neuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 [PubMed 1321422]).
Ver Producto
Neuropeptide Y Receptor Y1 (NPY1R) Antibody
NPY1R Antibody is a Rabbit Polyclonal antibody against NPY1R.
Ver Producto