Rat Myosin Light Chain Kinase 2 (MYLK2) ELISA Kit
715€ (96 tests)
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name
Rat Myosin Light Chain Kinase 2 (MYLK2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx534195
tested applications
ELISA
Description
Rat Myosin Light Chain Kinase 2 (MYLK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Myosin light chain kinase 2, skeletal/cardiac muscle concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Myosin Light Chain Kinase 2 (MYLK2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P20689 |
| Alias | KMLC,MLCK,MLCK2,skMLCK,Myosin light chain kinase 2, skeletal cardiac muscle |
| Background | Elisa kits for MYLK2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Myosin light chain kinase 2 (MYLK2) is a muscle-specific isoform of myosin light chain kinase predominantly expressed in skeletal muscle tissue. MYLK2 plays a key role in regulating myosin activity during muscle contraction by phosphorylating the regulatory light chains of myosin II, a process critical for force generation and sarcomere function. The kinase activity of MYLK2 is tightly regulated by calcium-calmodulin signaling, ensuring precise control of contractile responses during dynamic skeletal muscle activities such as exercise and locomotion. MYLK2 also contributes to the adaptive remodeling of muscle fibers in response to mechanical stress and physiological demands. Mutations or dysregulation of MYLK2 have been associated with myopathies and muscle weakness, emphasizing its essential role in maintaining muscular integrity and function.
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