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Rat Mucin 1 (MUC1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
675€ (96 tests)
Elisa Kits MUC1
proveedor
Abbexareference
abx155846Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Mucin 1 / CA15-3 / KL-6 (MUC1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Mucin 1 / CA15-3 / KL-6 (MUC1) concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Mucin 1No significant cross-reactivity or interference between Mucin 1 and analogues was observed.
Background
MUC1 (Mucin 1) is a large, transmembrane glycoprotein predominantly expressed on the surface of epithelial cells in various tissues, including the lungs, stomach, intestines, and the mammary glands. As a mucin protein, MUC1 plays a critical role in forming a protective mucous barrier on epithelial surfaces, which protects against environmental and microbial challenges. MUC1 also contributes to cell signaling and modulation of the immune response, particularly in epithelial cell inflammation. Due to its protective function on epithelial tissues, MUC1 expression is typically restricted to the apical surface of cells. However, in pathological states like cancer, MUC1 expression becomes dysregulated. Overexpression, aberrant glycosylation, and loss of polarity are commonly observed in many epithelial cancers, including breast, ovarian, and pancreatic cancers. These modifications contribute to tumor development, cancer cell survival, and metastasis, making MUC1 a key target for cancer diagnostics and therapeutics. In addition to cancer, MUC1 is associated with certain inflammatory and infectious diseases due to its role in the immune system.
Características del producto
category
ELISA Kits
immunogen target
Mucin 1 (MUC1)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.13 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Cancer antigen 15-3,CA 15-3,EMA,MCD,PEM,PUM,KL-6,MAM6,MCKD,PEMT,CD227,H23AG,MCKD1,MUC-1,ADMCKD, ADTKD2,Ca15-3,MUC-1,Episialin
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
MUC1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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