Rat Microtubule Associated Protein 2 (MAP2) Protein

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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein MAP2
proveedor
Abbexareference
abx068014Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Microtubule Associated Protein 2 (MAP2) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
Microtubule-associated protein 2 (MAP2) is a protein primarily found in neurons, where it plays a crucial role in stabilizing microtubules, maintaining cell shape, and supporting dendritic development MAP2 is part of a family of microtubule-associated proteins that bind to microtubules and regulate their stability, thereby contributing to the structural integrity of the cytoskeleton In neurons, MAP2 is essential for dendritic growth and synaptic plasticity, as it helps organize microtubules that extend into dendritic spines, the sites of synaptic connections and communication Dysregulation or loss of MAP2 function is associated with neurodegenerative diseases such as Alzheimer's disease and tauopathies, where disrupted microtubule stability leads to impaired neuronal function and neurofibrillary tangles MAP2 also serves as a marker for dendritic structures in neurons and is important for maintaining the organization of the central nervous system during development and in response to injury
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Microtubule Associated Protein 2 (MAP2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 58.1 kDa Observed MW (SDS-PAGE): 58 kDa Concentration: Prior to lyophilization: 180 µg/ml Sequence Fragment: Thr1459-Arg1718 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 80%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
MAP2
dry ice
No
availability
Shipped within 5-12 working days.
alias
MAP-2,MAP2A,MAP2B,MAP2C
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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