Rat Map2(Microtubule-associated protein 2) ELISA Kit

Este producto es parte de MAP2 - microtubule associated protein 2
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935106861
info@markelab.com
name
Rat Map2(Microtubule-associated protein 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0506

Documents del producto

Instrucciones
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Data sheet

Product specifications

Category
ELISA Kits
Reactivity
rat
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Size 1
96T
Sample Type
Serum,Plasma,Tissue homogenates,Other biological fluids
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
P15146
Alias
MAP-2,MAP2A,MAP2B,MAP2C
Background
Elisa Kits MAP2
Status
RUO

Microtubule-associated protein 2 (MAP2) is a protein primarily found in neurons, where it plays a crucial role in stabilizing microtubules, maintaining cell shape, and supporting dendritic development MAP2 is part of a family of microtubule-associated proteins that bind to microtubules and regulate their stability, thereby contributing to the structural integrity of the cytoskeleton In neurons, MAP2 is essential for dendritic growth and synaptic plasticity, as it helps organize microtubules that extend into dendritic spines, the sites of synaptic connections and communication Dysregulation or loss of MAP2 function is associated with neurodegenerative diseases such as Alzheimer's disease and tauopathies, where disrupted microtubule stability leads to impaired neuronal function and neurofibrillary tangles MAP2 also serves as a marker for dendritic structures in neurons and is important for maintaining the organization of the central nervous system during development and in response to injury

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This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.

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