Rat Macrophage Scavenger Receptor 1 (MSR1) Protein
1118€ (100 µg)
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Name
Rat Macrophage Scavenger Receptor 1 (MSR1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx693212
Tested Applications
SDS-PAGE
Description
Rat MSR1 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat MSR1 (NP_001178868.1) (Trp79-Ser454) was expressed with a polyhistidine tag at the N-terminus.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | MSR1 |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Trp79-Ser454 Tag: N-terminal His tag |
| Origin | Rat |
| Observed MW | 43.1 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_001178868.1 |
| Alias | Macrophage scavenger receptor types I and II,SRA,SR-A,CD204,SR-AI,phSR1,phSR2,SCARA1,SR-AII,SR-AIII,Macrophage acetylated LDL receptor I and II,Scavenger receptor class A member 1 |
| Background | Protein MSR1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Background
Macrophage Scavenger Receptor 1 (MSR1), also known as CD204, is a multifunctional receptor primarily expressed on macrophages and other cells of the mononuclear phagocyte system. MSR1 is a critical player in the immune system, where it recognizes and binds to various ligands, including modified lipoproteins, pathogens, and apoptotic cells, thereby aiding in host defense, tissue homeostasis, and inflammation. MSR1 functions by clearing endogenous and exogenous substances from the bloodstream and tissues, including oxidized low-density lipoproteins (oxLDL), a process essential in preventing atherosclerosis and other inflammatory diseases. Due to its role in these processes, MSR1 has been studied extensively in the context of immune responses, pathogen recognition, and chronic inflammatory conditions, including cardiovascular diseases and cancer.
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