Rat Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit

Este producto es parte de LPAR - Lysophosphatidic Acid Receptor
Rat Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LPAR1

proveedor

Abbexa

reference

abx521314

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Lysophosphatidic acid receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

LPAR1 is a G protein-coupled receptor activated by lysophosphatidic acid (LPA), a bioactive phospholipid involved in diverse cellular processes. LPAR1 is widely expressed in various tissues, including the brain, lungs, and fibroblasts, where it mediates cell proliferation, survival, migration, and cytoskeletal reorganization. LPAR1 couples to multiple G proteins (Gi, Gq, and G12/13), activating pathways such as MAPK, Rho/ROCK, and PI3K/Akt. In fibrosis, LPAR1 signaling promotes fibroblast activation and extracellular matrix deposition, contributing to pulmonary, hepatic, and renal fibrosis. It is also implicated in neuropathic pain, where LPAR1 activation sensitizes pain pathways and amplifies neuronal signaling. In cancer, LPAR1 drives tumor growth, metastasis, and angiogenesis, particularly in breast and lung cancers. Dysregulation of LPAR1 is associated with inflammatory disorders, cancer progression, and fibrosis. LPAR1 antagonists are being developed as potential therapies for fibrotic diseases, neuropathic pain, and cancer, highlighting its role as a key modulator of cell migration and tissue remodeling.

Características del producto

category

ELISA Kits


immunogen target

Lysophosphatidic Acid Receptor 1 (LPAR1)


reactivity

Rat


test range

0.312 ng/ml - 20 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

LPAR1,EDG2,LPA1,VZG1,edg-2,vzg-1,Gpcr26,Mrec1.3,rec.1.3,GPR26,endothelial differentiation gene 2,lysophosphatidic acid G-protein-coupled receptor, 2,LPA receptor 1,lysophosphatidic acid receptor Edg-2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LPAR1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


Quizá le pueda interesar

Human LPAR1(Lysophosphatidic acid receptor 1) ELISA Kit

Human LPAR1(Lysophosphatidic acid receptor 1) ELISA Kit

proveedor

FineTest

reference

EH2508

reactivity

human

status

RUO

Precio a consultar

Ver más

LPA Receptor 1 Antibody

LPA Receptor 1 Antibody

proveedor

Abbexa

reference

abx019130

Tested Applications

WB

reactivity

Mouse

status

RUO

clonality

Polyclonal

LPA Receptor 1 Antibody is a Rabbit Polyclonal antibody against Mouse.

312€ (100 µg)

Ver más

Human Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit

Human Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit

proveedor

Abbexa

reference

abx152223

Tested Applications

ELISA

reactivity

Human

status

RUO

Human Lysophosphatidic Acid Receptor 1 (LPAR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hu...

715€ (96 tests)

Ver más