Rat Low Density Lipoprotein Receptor Related Protein 1 (LRP1) ELISA Kit

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935106861
info@markelab.com
Precio
611€ (96 tests)
Elisa kits for LRP1
proveedor
Abbexareference
abx054845Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Low Density Lipoprotein Receptor Related Protein 1 (LRP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat LRP-1 concentrations in serum, plasma and other biological fluids.
Background
Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) is a multifunctional cell surface receptor with diverse roles in cellular processes, including endocytosis, lipid transport, signal transduction, and the regulation of inflammation. Part of the low-density lipoprotein (LDL) receptor family, LRP1 has high sequence homology with the LDL receptor but a much broader set of ligands, facilitating interactions with various proteins, such as apolipoprotein E (ApoE), tissue plasminogen activator (tPA), and matrix metalloproteinases. LRP1 is highly expressed in the liver, brain, and adipose tissues, where it plays crucial roles in metabolism, neuroprotection, and vascular health. In neurons, LRP1 mediates neuroprotective processes and is implicated in the clearance of amyloid-beta, a key protein in Alzheimer’s disease pathology. In addition to metabolic and neural roles, LRP1 impacts cellular migration and adhesion, contributing to processes related to tissue injury repair, cancer metastasis, and inflammatory diseases. Its function and widespread expression make LRP1 a focal point in therapeutic research for conditions including neurodegenerative diseases, atherosclerosis, and certain cancers.
Características del producto
category
ELISA Kits
immunogen target
Low Density Lipoprotein Receptor Related Protein 1 (LRP1)
reactivity
Rat
test range
0.31 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Prolow-density lipoprotein receptor-related protein 1,Alpha-2-macroglobulin receptor,APR,KPA,LRP,A2MR,CD91; DDH3,APOER,LRP1A,TGFBR5,IGFBP3R,IGFBP-3R,IGFBP3R1,LRP-1,Apolipoprotein E receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
LRP1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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