Rat Long-Chain-Fatty-Acid-CoA Ligase 6 (ACSL6) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Long-Chain-Fatty-Acid-CoA Ligase 6 (ACSL6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx500889
tested applications
ELISA
Description
Rat Long-Chain-Fatty-Acid-CoA Ligase 6 (ACSL6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Long-chain-fatty-acid--CoA ligase 6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Long-Chain-Fatty-Acid-CoA Ligase 6 (ACSL6) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P33124 |
| Alias | ACS2,FACL6,LACS 6,LACS2 |
| Background | Elisa kits for ACSL6 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACSL6 is a long-chain acyl-CoA synthetase that preferentially activates polyunsaturated fatty acids, such as docosahexaenoic acid (DHA) and arachidonic acid, by converting them into acyl-CoA derivatives. It is predominantly expressed in the brain, erythrocytes, and testes, where it supports specialized lipid metabolism required for neuronal function, erythrocyte membrane integrity, and spermatogenesis. In the brain, ACSL6 plays a crucial role in synthesizing and maintaining membrane lipids enriched with polyunsaturated fatty acids, which are essential for synaptic plasticity and neuronal communication. Dysregulation of ACSL6 has been linked to neurodegenerative diseases, such as schizophrenia and bipolar disorder, as well as hematological disorders due to its involvement in erythrocyte lipid composition. Its activity underscores its importance in maintaining cellular lipid homeostasis, particularly in tissues with high polyunsaturated fatty acid content.
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