Rat Leucine-Rich Repeat-Containing Protein 7 (LRRC7) ELISA Kit

Este producto es parte de LRRC - Leucine-rich repeat-containing protein
Rat Leucine-Rich Repeat-Containing Protein 7 (LRRC7) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for LRRC7

proveedor

Abbexa

reference

abx531575

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat Leucine-Rich Repeat-Containing Protein 7 (LRRC7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Leucine-rich repeat-containing protein 7 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

LRRC7, also known as Densin-180, is a postsynaptic scaffolding protein enriched in the brain, where it regulates synaptic organization, signaling, and plasticity. It interacts with key proteins such as PSD-95, CaMKII, and actin regulators to stabilize and organize the postsynaptic density (PSD) at excitatory synapses. LRRC7 plays an essential role in dendritic spine maturation, synaptic strength, and calcium signaling, contributing to processes like learning, memory, and neuronal development. It is particularly abundant in regions like the hippocampus and cortex, where synaptic plasticity is critical. Dysregulation or mutations in LRRC7 are associated with neurodevelopmental disorders, including intellectual disabilities and autism spectrum disorders (ASD), due to impaired synaptic connectivity and function. Knockout studies in mice reveal altered dendritic spine morphology, impaired synaptic transmission, and deficits in learning and memory, highlighting its essential role in maintaining synaptic structure and cognitive function.

Características del producto

category

ELISA Kits


immunogen target

Leucine-Rich Repeat-Containing Protein 7 (LRRC7)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

Densin-18,Densin,Protein LAP1,KIAA1365, LAP1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

LRRC7


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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