Rat Leucine-Rich Repeat-Containing Protein 56 (LRRC56) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Leucine-Rich Repeat-Containing Protein 56 (LRRC56) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531439
tested applications
ELISA
Description
Rat Leucine-Rich Repeat-Containing Protein 56 (LRRC56) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Leucine-rich repeat-containing protein 56 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-Rich Repeat-Containing Protein 56 (LRRC56) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q4V8C9 |
| Alias | CILD39,DNAAF12,oda8 |
| Background | Elisa kits for LRRC56 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRRC56 is a leucine-rich repeat-containing protein that functions as a critical regulator of cilia motility by facilitating the assembly of axonemal dynein arms, which are required for the beating of motile cilia. It localizes to the ciliary structure and interacts with proteins involved in dynein arm assembly and transport, enabling the proper function of motile cilia in tissues such as respiratory epithelium, brain ependyma, and reproductive organs. LRRC56 is essential for the coordinated beating of cilia, contributing to mucus clearance, fluid movement, and sperm motility. Mutations in LRRC56 are associated with primary ciliary dyskinesia (PCD), a condition characterized by chronic respiratory infections, reduced fertility, and hydrocephalus due to defective ciliary motility. Knockout studies reveal disrupted dynein arm assembly, immotile cilia, and impaired fluid movement, highlighting its critical role in ciliary function and the maintenance of tissue homeostasis.
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