Rat Leucine-Rich Repeat-Containing Protein 56 (LRRC56) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits LRRC56
proveedor
Abbexareference
abx531439Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Leucine-Rich Repeat-Containing Protein 56 (LRRC56) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Leucine-rich repeat-containing protein 56 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
LRRC56 is a leucine-rich repeat-containing protein that functions as a critical regulator of cilia motility by facilitating the assembly of axonemal dynein arms, which are required for the beating of motile cilia. It localizes to the ciliary structure and interacts with proteins involved in dynein arm assembly and transport, enabling the proper function of motile cilia in tissues such as respiratory epithelium, brain ependyma, and reproductive organs. LRRC56 is essential for the coordinated beating of cilia, contributing to mucus clearance, fluid movement, and sperm motility. Mutations in LRRC56 are associated with primary ciliary dyskinesia (PCD), a condition characterized by chronic respiratory infections, reduced fertility, and hydrocephalus due to defective ciliary motility. Knockout studies reveal disrupted dynein arm assembly, immotile cilia, and impaired fluid movement, highlighting its critical role in ciliary function and the maintenance of tissue homeostasis.
Características del producto
category
ELISA Kits
immunogen target
Leucine-Rich Repeat-Containing Protein 56 (LRRC56)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
CILD39,DNAAF12,oda8
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LRRC56
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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